Combining magnetism and light to fight cancer

Paris, 24 March 2015

Combining magnetism and light to fight cancer

By combining, in a liposome1, magnetic nanoparticles and photosensitizers that are simultaneously and remotely activated by external physical stimuli (a magnetic field and light), scientists at the Laboratoire Matière et Systèmes Complexes (CNRS/Université Paris Diderot) and the Laboratoire Physicochimie des Electrolytes et Nanosystèmes Interfaciaux (CNRS/UPMC),2 obtained total tumor regression in mice. Non-toxic when they are not activated, such therapies can also achieve a reduction in adverse effects. These results, which demonstrate the importance of multiple treatments, were published in ACS Nano on 24 March 2015.

To download the press release: Magnetisme_Lumiere_Cancer

Notes:

1A liposome is an artificial vesicle whose internal compartment is formed by lipid bilayers. 
2In collaboration with scientists from the Paris-Centre de Recherche Cardiovasculaire (Inserm/Université Paris Descartes)

References:

Combining Magnetic Hyperthermia and Photodynamic Therapy for Tumor Ablation with Photoresponsive Magnetic Liposomes
Riccardo Di Corato, Gaëlle Béalle, Jelena Kolosnjaj-Tabi, Ana Espinosa, Olivier Clément, Amanda K. A. Silva, Christine Ménager, et Claire Wilhelm. ACS nano, 24 March 2015. DOI : 10.1021/nn506949t.

Contact information:

Scientist l Claire Wilhelm l T 01 57 27 62 53 lclaire.wilhelm@univ-paris-diderot.fr 
Scientistl Christine Ménager l T 01 44 27 30 47 lchristine.menager@upmc.fr 
CNRS press l Alexiane Agullo l T 01 44 96 43 90 lalexiane.agullo@cnrs-dir.fr
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